diff --git a/README.md b/README.md
index 84e51d08e75f06cae2c1ad328d2c60fec194edfb..39af022f3aeadab81733f8fd047d4b3a4dc2bb8f 100644
--- a/README.md
+++ b/README.md
@@ -11,7 +11,7 @@ If you want to use the pipeline, please follow the following easy instructions:
 2. Use the `examples/templates` folder to quickly get started with examples for the genome of your choice and prepare your dataset. In addition, you can check the `examples/input` folder.
 3. Create a new conda / mamba environment in which you install the newest version of snakemake. Follow the snakemake installation instructions from the official website. Nothing else is needed, as our pipeline uses pre-build Singularity containers that contain all required software.
 4. Download the additional annotation and resource files that are required - see the config.yaml and also the separate instructions here below. You may also use your own versions, of course, but we do have and can provide example files for your genome assembly.
-6. Run the pipeline by executing snakemake - see the separate instructions for this.
+6. Run the pipeline by executing snakemake - either use the wrapper scripts we provide or run snakemake manually on your own. See the file `Documentation.pdf` in the doc folder for more details.
 
 **For parameter explanation, see the explanations in the config yaml files.**