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## Dependencies
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LocScale is written in [Python](https://www.python.org/) and in part based on libraries from [SPARX](http://sparx-em.org) and [CCTBX](https://github.com/cctbx/cctbx_project).
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LocScale is written in [Python](https://www.python.org/) and in part based on libraries from [EMAN2/SPARX](http://sparx-em.org) and [CCTBX](https://github.com/cctbx/cctbx_project).
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LocScale is dependent on [NumPy and SciPy](http://www.numpy.org/) and [mpi4py](http://pythonhosted.org/mpi4py/).
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## Installation
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## Documentation
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##### Please see the Wiki pages for
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Please consult the Wiki pages for instructions on:
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- [Generation of reference map](Model_map_generation)
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- [Generation of LocScale maps](Locscale)
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#### [__LocScale__](LocScale) - local sharpening based on reference-based amplitude scaling
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#### The program is available [here] (https://git.embl.de/jakobi/LocScale/tree/master/download) for download.
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<br>
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## References
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[[1]](https://doi.org/10.1101/121913) Jakobi et al. bioRxiv 121913 (2017) |
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