Commit 5640d9ca authored by Bernd Klaus's avatar Bernd Klaus

modifications and updates for the April 18 course

parent e0880027
......@@ -886,8 +886,8 @@ single cell data RNA--Seq data is commonly thought to contain more zeros
than predicted by the NB distribution. As the additional zeros are believed
to be due to technical factors such the efficiencies of reverse transcription,
these additional zeros are also known as "dropouts".^[On the other hand,
the NB model does not seem to be too bad for sc Data, see e.g. [Valentine Svensson 's](http://www.nxn.se/valent/2017/11/16/droplet-scrna-seq-is-not-zero-inflated) blog
post on this matter.]
the NB model does not seem to be too bad for sc Data, see e.g. [Valentine Svensson 's] blog
posts on this matter [here](http://www.nxn.se/valent/2017/11/16/droplet-scrna-seq-is-not-zero-inflated) and [here](http://www.nxn.se/valent/2018/1/30/count-depth-variation-makes-poisson-scrna-seq-data-negative-binomial).]
The proportion of zeros is modeled by \(\pi\) while \(mu\) are the counts.
......
This diff is collapsed.
Markdown is supported
0% or
You are about to add 0 people to the discussion. Proceed with caution.
Finish editing this message first!
Please register or to comment