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Martin Larralde
pyrodigal
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4ab8b55d
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4ab8b55d
authored
Feb 26, 2022
by
Martin Larralde
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Reword some sentences in the `Statement of need` section
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@@ -44,15 +44,16 @@ To address these issues, we developed Pyrodigal, a Python module implemented
in Cython [@Cython] that binds to the Prodigal internals, resulting in identical
predictions and similar performance through a friendly object-oriented interface.
The predicted genes are returned as Python objects, with properties for retrieving
confidence scores or coordinates, and methods for translating the gene sequence.
Prodigal is compiled from source and statically linked into a compiled Python
extension, which allows it to be installed with a single
`pip install`
command,
even on a target machine that requires compilation.
Pyrodigal has already been used as the initial ORF finding method in several
domains, including biosynthetic gene cluster prediction [@GECCO:2021],
prophage identification [@PhageBoost:2021; @hafeZ:2021], and pangenome
analysis [@AlphaMine:2021].
confidence scores or coordinates, and methods for translating the gene sequence
with a default or user-provided translation table. Prodigal is compiled from
source and statically linked into a compiled Python extension, which allows
it to be installed with a single
`pip install`
command, even on a target
machine that requires compilation.
Pyrodigal has already been used as the implementation for the initial ORF
finding stage in several domains, including biosynthetic gene cluster
prediction [@GECCO:2021], prophage identification [@PhageBoost:2021; @hafeZ:2021],
and pangenome analysis [@AlphaMine:2021].
# Method
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