... | ... | @@ -4,4 +4,4 @@ Confidence maps are complementary maps generated from common EM maps and aim to |
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Confidence maps provide a way to set a objective contour level and at the same time give an error criterion associated with the density. Especially building and interpretation of difficult features like small molecule ligands, water molecules and ions is facilitated. The usage is not limited to near-atomic resolution maps, as confidence maps from lower resolution sub-tomogram averages have been shown to provide similar advantages for density interpretation, especially when working with noisy data generated from a small amount of sub-tomograms.
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The statistical framework allows the incorporation of local resolution and atomic model information in order to increase the power of the test procedure. Especially when dealing with extensive resolution variations the consideration of prior information can be beneficial. |
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The statistical framework allows the incorporation of local resolution and atomic model information in order to increase the power of the test procedure. Especially when dealing with extensive resolution variations the consideration of prior spatial information can be beneficial. |
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