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## What is LocScale?
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## About
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LocScale is a reference-based local amplitude scaling tool that used prior model information to improve contrast of cryo-EM density maps.
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| ... | ... | @@ -9,17 +9,20 @@ To reliably reflect the required level of local sharpening and local resolution |
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<img src="https://git.embl.de/jakobi/LocScale/raw/master/doc/img/EM_cyle_DM_1.jpg" width="400">
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<br>
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#### [__LocRes__](LocRes) - local resolution estimation based on windowed FSC calculation
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#### [__LocScale__](LocScale) - local sharpening based on reference-based amplitude scaling
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<br>
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#### The program is available here for [Download ](https://git.embl.de/jakobi/LocScale/tree/master/download).
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#### The program is available [here] (https://git.embl.de/jakobi/LocScale/tree/master/download) for download.
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<br>
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[//]: # (#### [__LocRes__](LocRes) - local resolution estimation based on windowed FSC calculation)
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[//]: # ([__LocFSC__](LocFSC) - local model validation based on FSC<sub>ref</sub> calculations)
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## Dependencies
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LocScale is written in [Python](https://www.python.org/) and in part based on libraries from [SPARX](http://sparx-em.org) and [CCTBX](https://github.com/cctbx/cctbx_project).
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LocScale is dependent on [NumPy and SciPy](http://www.numpy.org/) and [mpi4py](http://pythonhosted.org/mpi4py/).
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LocScale
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[[1]](https://doi.org/10.1101/121913) Jakobi et al. bioRxiv 121913 (2017) |
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