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Producing locally contrast-optimized maps using LocScale requires a reference model map that accurately reflects the variation in resolution expressed in atomic B-factors. We therefore recommend to first perform coordinate and ADP refinement against a globally sharpened and (locally) filtered map as described the bioRxiv preprint [1].
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Producing locally contrast-optimized maps using LocScale requires a reference model map that accurately reflects the variation in resolution expressed in atomic B-factors. We therefore recommend to first perform coordinate and ADP refinement against a globally sharpened and (locally) filtered map as described the bioRxiv preprint [1].
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