Initial verison of Readme

README.md

 # Genetic Interactions Screen on Lipid Levels
 
+## Project Overview
+
+This repository contains protocols for the data analysis for analysing the gene interaction data for LDL uptake screen.
+
+## Repository content
+- Image analysis results of RNAi screen (Image analysis performed with [CellProfiler](https://cellprofiler.org/), data quality control and calculation of z-scores performed with [HTMExplorer](https://github.com/tischi/HTM_Explorer)).
+- Statistical analysis of RNAi screen data.
+- Statistical analysis of genetic data. 
+
+## Contributors
+- Magdalena Zimon (Pepperkok Lab, EMBL): RNAi experiments and analysis, current project maintainer.
+- Yunfeng Huang (Biogen): statistical analysis of genetic data.
+- Anthi Trasta (Pepperkok Lab, EMBL): primary RNAi screen and statistical analysis.
+- Aliaksandr Halavatyi (ALMF, EMBL): statistical data analysis and support.
+
+## Citation
+
+These work is part of the manuscript:
+
+> Genetic interactions modulate lipid plasma levels and cellular uptake. Magdalena Zimon, Yunfeng Huang, Anthi Trasta, Jimmy Liu, Chia-Yen Chen, Aliaksandr Halavatyi, Peter Blattmann, Bernd Klaus, Chris Whelan, David Sexton, Sally John, Ellen Tsai, Wolfgang Huber, Rainer Pepperkok, Heiko Runz
+
+## Acknowledgement
+We thank Bernd Klaus (CSDA, EMBL) for the essential advises on statistical analysis
+