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protein-bioinformatics-nov-2016
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Benjamin Lang
protein-bioinformatics-nov-2016
Commits
1edb2313
Commit
1edb2313
authored
8 years ago
by
Marc Gouw
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Added piratenpad program to README
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## Program
For now, please check the Piraten Pad: https://piratenpad.de/p/gibson_workshops
\ No newline at end of file
**Part-1 Protein databases and sequence analysis**
1.
Protein databases: Malvika
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NCBI (very quick overview)
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UniProt
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Swissprot
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Cross-refrences and link-outs
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OMIM, Domains, GO, ...
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Trembl
2.
Study of similar sequences: Marc
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BLAST
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BLASTp, BLASTn, PSI-BLAST,
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HHPred
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HMMER
3.
Multiple sequence alignments: Manjeet
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UniProt aligner
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EMBOSS dot-plot
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Muscle, Clustal omega
4.
Other resources: Toby & Malvika
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Human portein atlas
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Antibodypedia
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EMBOSS toolkits
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Pepinfo
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Sixpack
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dotmatcher: http://emboss.bioinformatics.nl/cgi-bin/emboss/dotmatcher
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Prediction of transmembrane helices in proteins: (This is a bit misplaced)
TMHMM (http://www.cbs.dtu.dk/services/TMHMM/)
**Part-2 Protein structure analysis**
*
Toby's keynote:
*
Secondary vs tertiary structure vs protein complexes (Theory)
1.
Structure database: Toby
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PDB (http://www.rcsb.org/pdb/home/home.do)
2.
Structure visualization: Toby
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Motif visualization:
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Jalview, MEME, Weblogo, Chimera (https://screenshots.debian.net/package/chimera2)
3.
Structure prediction: ???
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jpred (http://www.compbio.dundee.ac.uk/jpred/)
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Jalview linked tool Janet (?)
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PSIpred (?)
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Tertiary structure prediction
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I-TASSER
4.
Domain databases: Ben
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InterPro,
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Pfam
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SCOP
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SMART?
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SUPERFAMILY?
5.
Intrinsically disordered region : Marc
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ELM ( http://elm.eu.org)
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IUPRED (http://iupred.enzim.hu)
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DISPROT?
6.
Protein-protein interaction: Malvika
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STRING (http://string-db.org)
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BioGrid?
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MINT?
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